Nicotinamide adenine dinucleotide phosphate oxidase 2 deletion attenuates polyhexamethylene guanidine-induced lung injury in mice
Inhalation of polyhexamethylene guanidine phosphate (PHMG) can cause pulmonary fibrosis.Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are enzymes that produce reactive oxygen species, which may be involved in tissue damage in various lung diseases.To investigate whether the Nox2 isoform of Nox is involved in the progression of